We've got an 80 PLUS Platinum supply in the form of the be quiet, another 80 PLUS Gold, albeit lower capacity, from Corsair, and an 80 PLUS Bronze of roughly equivalent capacity from Rosewill.
The ideal scenario is to have these numbers as close to 12V as possible. Supplies always over-volt with little load and then sag to some degree when at full tilt. Any figure above 11.8V, at their respective full loads, is considered fine.
Cross-loads are harder for a PSU to deal with because voltage is being concurrently applied to different rails at one time. Think of it as loading up your CPU, graphics and peripherals all in one go - a worst-case scenario.
Cross-load 1 puts almost all of the capacity down the throat of the 12V line while also stressing the 3.3V/5V lines with a couple of amps. The reverse is true of cross-load 2.
The upshot, in terms of regulation, is voltage straying a little farther away from the perfect 12V. The XFX is competitive in both scenarios.