Fallout 4
Introduced as the fifth major entry in the series, Fallout 4 takes place in post-apocalyptic Boston in the year 2287, 210 years after a Nuclear war. Not the most uplifting environment, but there are plenty of open environments to explore and the visuals, especially on PC, are at times dazzling.
Some games are more challenging than others. Even a GTX 1080 can't muster 60 frames per second in Fallout 4 at a 4K UHD resolution.